Package: Canek 0.2.5

Canek: Batch Correction of Single Cell Transcriptome Data

Non-linear/linear hybrid method for batch-effect correction that uses Mutual Nearest Neighbors (MNNs) to identify similar cells between datasets. Reference: Loza M. et al. (NAR Genomics and Bioinformatics, 2020) <doi:10.1093/nargab/lqac022>.

Authors:Martin Loza [aut, cre], Diego Diez [aut]

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Canek.pdf |Canek.html
Canek/json (API)
NEWS

# Install 'Canek' in R:
install.packages('Canek', repos = c('https://martinloza.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Bug tracker:https://github.com/martinloza/canek/issues

Datasets:
  • SimBatches - Dataset with simulated single cell RNA-seq from 2 batches.

On CRAN:

batch-effectsbioinformaticssingle-cell-rna-seqtranscriptomics

5.54 score 5 stars 23 scripts 240 downloads 3 exports 43 dependencies

Last updated 10 months agofrom:26075598fe. Checks:OK: 6 WARNING: 1. Indexed: yes.

TargetResultDate
Doc / VignettesOKOct 31 2024
R-4.5-winOKOct 31 2024
R-4.5-linuxWARNINGOct 31 2024
R-4.4-winOKOct 31 2024
R-4.4-macOKOct 31 2024
R-4.3-winOKOct 31 2024
R-4.3-macOKOct 31 2024

Exports:CorrectBatchCorrectBatchesRunCanek

Dependencies:assortheadBHBiocGenericsBiocNeighborsBiocParallelblusterclasscliclustercodetoolscpp11DEoptimRdiptestflexmixFNNformatRfpcfutile.loggerfutile.optionsgenericsglueigraphirlbakernlablambda.rlatticelifecyclemagrittrMASSMatrixmatrixStatsmclustmodeltoolsnnetnumberspkgconfigprabclusRcpprlangrobustbaseS4Vectorssnowvctrs

Run Canek on a toy example

Rendered fromtoy_example.Rmdusingknitr::rmarkdownon Oct 31 2024.

Last update: 2022-03-22
Started: 2021-06-17

Readme and manuals

Help Manual

Help pageTopics
CheckZeroCVCheckZeroCV
CorrectBatchCorrectBatch
CorrectBatchesCorrectBatches
Correction vector estimationEkfBE
Title FuzzyFuzzy
MeanBEMeanBE
Correction vector estimationMedianBE
Title PairsFilteringPairsFiltering
RunCanekRunCanek RunCanek.list RunCanek.Seurat RunCanek.SingleCellExperiment
Dataset with simulated single cell RNA-seq from 2 batches.SimBatches