Package: Canek 0.2.5

Canek: Batch Correction of Single Cell Transcriptome Data

Non-linear/linear hybrid method for batch-effect correction that uses Mutual Nearest Neighbors (MNNs) to identify similar cells between datasets. Reference: Loza M. et al. (NAR Genomics and Bioinformatics, 2020) <doi:10.1093/nargab/lqac022>.

Authors:Martin Loza [aut, cre], Diego Diez [aut]

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Canek.pdf |Canek.html
Canek/json (API)
NEWS

# Install 'Canek' in R:
install.packages('Canek', repos = c('https://martinloza.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Bug tracker:https://github.com/martinloza/canek/issues

Datasets:
  • SimBatches - Dataset with simulated single cell RNA-seq from 2 batches.

On CRAN:

batch-effectsbioinformaticssingle-cell-rna-seqtranscriptomics

3 exports 5 stars 1.60 score 42 dependencies 23 scripts 322 downloads

Last updated 8 months agofrom:26075598fe. Checks:OK: 7. Indexed: yes.

TargetResultDate
Doc / VignettesOKAug 21 2024
R-4.5-winOKAug 21 2024
R-4.5-linuxOKAug 21 2024
R-4.4-winOKAug 21 2024
R-4.4-macOKAug 21 2024
R-4.3-winOKAug 21 2024
R-4.3-macOKAug 21 2024

Exports:CorrectBatchCorrectBatchesRunCanek

Dependencies:BHBiocGenericsBiocNeighborsBiocParallelblusterclasscliclustercodetoolscpp11DEoptimRdiptestflexmixFNNformatRfpcfutile.loggerfutile.optionsglueigraphirlbakernlablambda.rlatticelifecyclemagrittrMASSMatrixmatrixStatsmclustmodeltoolsnnetnumberspkgconfigprabclusRcppRcppHNSWrlangrobustbaseS4Vectorssnowvctrs

Run Canek on a toy example

Rendered fromtoy_example.Rmdusingknitr::rmarkdownon Aug 21 2024.

Last update: 2022-03-22
Started: 2021-06-17

Readme and manuals

Help Manual

Help pageTopics
CheckZeroCVCheckZeroCV
CorrectBatchCorrectBatch
CorrectBatchesCorrectBatches
Correction vector estimationEkfBE
Title FuzzyFuzzy
MeanBEMeanBE
Correction vector estimationMedianBE
Title PairsFilteringPairsFiltering
RunCanekRunCanek RunCanek.list RunCanek.Seurat RunCanek.SingleCellExperiment
Dataset with simulated single cell RNA-seq from 2 batches.SimBatches